In response to the existing issues of unclear command relationships, ambiguous information flow, and limited means of disposal in anti-submarine warfare, this study proposes mechanisms and modes for achieving victory in anti-submarine operations. It approaches the problem from three perspectives: the physical domain, the information domain, and the intelligent domain. Based on the dynamic and evolving OODA(observation,orientation,decision,action) operational loop theory, combined with an analysis of the current status and trends in anti-submarine equipment and operational styles, a concept design for manned-unmanned cooperative anti-submarine warfare is presented. Additionally, key technological requirements for intelligent domain anti-submarine warfare are summarized, aiming to provide insights for the future development of low-cost and efficient anti-submarine operations.