Missile stability control system is one of the crucial technologies to promote missile guidance performances, and has always been a research hotspot and focus. Taking the longitudinal plane of a missile as an example, a state-space model of the missile stability control is established. The linear quadratic regulator (LQR) control algorithm is derived, and an improved PID(proportional integral derivative)-LQR approach for missile stability control is proposed based on the traditional LQR method and PID algorithm. The control performances of the proposed method are compared with traditional LQR method, improved LQR method, and fuzzy PIQ-LQR method through simulation analysis. The established missile model parameters are subjected to conduct bias tests. The simulation results show that the proposed method is superior to the other three methods and has good control performances and robustness.